Tunicamycin : dnj-27

Treatment with 10, 20 and 30 μg/ml tunicamycin resulted in a strong increase of GFP fluorescence of Pdnj-27::GFP reporter.

MG132 : quercetin

"Additionally, inhibiting proteasomal degradation by use of the specific proteasome inhibitor MG132 (200 μM) completely blocked the rescuing effect of quercetin with respect to survival (Fig. 7D)."

rol-3 : rol-6

Animals were right-rollers as L3's, but squattish nonrollers as L4's and adults.

mig-14 : vps-35

There is a striking reduction in MIG-14::GFP protein levels in vps-35(hu68) mu- tants. Western blot analysis showed that MIG-14 protein levels are also reduced in vps-35 mutants.

F53A9.8 : Heat-Killed Staphylococcus Aureus : Y65B4BR.1 : clec-52 : clec-60 : clec-71 : cpr-2 : exc-5 : fmo-2 : ilys-3 : lys-5

"...We measured gene induction during exposure to live S. aureus, which causes pathogenesis, or heat-killed S. aureus, which does not (Figures 3G-I and S4C, E). Unexpectedly, all 10 biomarker genes were induced at least equally well on heat-killed S. aureus as on live S. aureus (Figure 6A)."

antimycin A : hsp-6

"We exposed the hsp-6 reporter strain from early L3 stage on for two days to 0.25 μM rotenone, which targets the ubiquinone of complex I, or to 0.25 μM antimycin A, which prevents electron transfer from coenzyme Q to cytochrome C. Both substances have been shown to increase the amount of ROS [33,36]. As with paraquat, both toxins caused an induction of the hsp-6 reporter (Figure 3A) being in line with the idea that an increase in mitochondrial ROS induces hsp-6."

hsp-6 : rotenone

"We exposed the hsp-6 reporter strain from early L3 stage on for two days to 0.25 μM rotenone, which targets the ubiquinone of complex I, or to 0.25 μM antimycin A, which prevents electron transfer from coenzyme Q to cytochrome C. Both substances have been shown to increase the amount of ROS [33,36]. As with paraquat, both toxins caused an induction of the hsp-6 reporter (Figure 3A) being in line with the idea that an increase in mitochondrial ROS induces hsp-6."

unc-33 : unc-44

UNC-33(S) accumulated at the nerve ring of control animals, and unc-44 mutants induced more diffuse distribution of UNC-33(S).

bacteria Staphylococcus aureus : irg-4

F08G5.6 was specifically induced by S. aureus-mediated infections.

erl-1 : hsp-4

"We examined GFP expression in hsp-4::GFP worms by Western blotting (Figure 8B). erl-1(tm2703) had no apparent effect on GFP expression either under basal conditions or following exposure to 5 μg/ml TN for various lengths of time."