"RNAi inhibition of CBP-1 induces ectopic expression of HLH-2::GFP in non-neuronal cells (Figure 4B, compare panels a and b; Shi and Mello, 1998), a promoter who's activity is restricted to neurons late in C. elegans embryogenesis (Krause et al., 1997). In contrast, inhibition of CBP-1 by RNAi eliminated the expression of HLH-1::GFP and ELT-2::GFP (Figure 4B, compare panels e and h with d and g), promoters that are active in muscle and endodermal cells, respectively (Krause et al., 1990; Fukushige et al., 1998)."
"RNAi inhibition of CBP-1 induces ectopic expression of HLH-2::GFP in non-neuronal cells (Figure 4B, compare panels a and b; Shi and Mello, 1998), a promoter who's activity is restricted to neurons late in C. elegans embryogenesis (Krause et al., 1997). In contrast, inhibition of CBP-1 by RNAi eliminated the expression of HLH-1::GFP and ELT-2::GFP (Figure 4B, compare panels e and h with d and g), promoters that are active in muscle and endodermal cells, respectively (Krause et al., 1990; Fukushige et al., 1998)."
"RNAi inhibition of CBP-1 induces ectopic expression of HLH-2::GFP in non-neuronal cells (Figure 4B, compare panels a and b; Shi and Mello, 1998), a promoter who's activity is restricted to neurons late in C. elegans embryogenesis (Krause et al., 1997). In contrast, inhibition of CBP-1 by RNAi eliminated the expression of HLH-1::GFP and ELT-2::GFP (Figure 4B, compare panels e and h with d and g), promoters that are active in muscle and endodermal cells, respectively (Krause et al., 1990; Fukushige et al., 1998)."
100% of embryos lack endoderm in double mutants at 15 deg C and 25 deg C, whereas lit-1 mutants only exhibit this phenotype at 25 deg C and mom-2 mutants exhibit this phenotype only partially at 22 deg C.