In a strong gld-2 loss-of-function allele(q497) CGH-1 was appropriately upregulated at meiosis entr y and appeared to be localized normally through the pachytene stage, but expression of both CGH-1 and PGL-1 was lost more proximally, in the abnormal gametes that are produced.
In a strong gld-2 loss-of-function allele(q497) CGH-1 was appropriately upregulated at meiosis entr y and appeared to be localized normally through the pachytene stage, but expression of both CGH-1 and PGL-1 was lost more proximally, in the abnormal gametes that are produced.
In a strong gld-2 loss-of-function allele(q497) CGH-1 was appropriately upregulated at meiosis entr y and appeared to be localized normally through the pachytene stage, but expression of both CGH-1 and PGL-1 was lost more proximally, in the abnormal gametes that are produced.
In a strong gld-2 loss-of-function allele(q497) CGH-1 was appropriately upregulated at meiosis entr y and appeared to be localized normally through the pachytene stage, but expression of both CGH-1 and PGL-1 was lost more proximally, in the abnormal gametes that are produced.
In a strong gld-2 loss-of-function allele(q497) CGH-1 was appropriately upregulated at meiosis entr y and appeared to be localized normally through the pachytene stage, but expression of both CGH-1 and PGL-1 was lost more proximally, in the abnormal gametes that are produced.
The mec-6 gene is required for the punctate distribution of MEC-4. When mec-4::yfp and promoter mec-4::cfp were injected into mec-6(u3) animals, the expression of the promoter mec-4::cfp fusion was unchanged, but the punctate expression from mec-4::y fp was undetectable.
"Using a-MEC-7 antibody (gift of G. Ruvkun, Massachusetts General Hospital, Boston, MA), we found MEC-7 expression in all four touch receptor neurons in wild-type embryos where it is detectable in both the cell body and axonal extensions. One such cell is shown in Figure 2e (the other three positive cells are in different focal planes). Five to 10 MEC-7-positive cells were found in terminal stage embryos lacking CBP-1 expression and these cells showed evidence of axon outgrowth consistent with neuronal differentiation (Fig. 2f)."