In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).
In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).
In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).
In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).
On the other hand, a hypomorphic brc-1 allele, brc-1(tm1145) (Li et al. 2018), in combination with hsr-9(xoe17) did not result in elevated embryonic lethality (Figure 1A).
In wild type, lin-32p::mRFP::unc-60A 3'UTR was intensely detected in every R(n).a + p. However, in plx-1 mutants, R(1).a + p, R(2).a + p and R(5).a + units displayed pronounced decreases in expression of mRFP.
In wild type, lin-32p::mRFP::unc-60A 3'UTR was intensely detected in every R(n).a + p. However, in smp-1smp-2 mutants, R(1).a + p, R(2).a + p and R(5).a + units displayed pronounced decreases in expression of mRFP.
Expression of mec-2-lacZ in the ALML/R, AVM, and PVM touch cells was greatly decreased (<5% of the cells stained); 67% of the PLML/R cells still stained in mec-3(u6).