tph-1 : zag-1

HSN GFP expression was rare or absent in zag-1 tph-1::gfp adult animals, whereas expression was unchanged in ADF, NSM, CP and R(1,3,9).

Lithium : lsd-1

Transcripts for T08D10.2, an amine oxidase and worm ortholog of human LSD-1, are reduced to 0.33 that of controls following Li treatment.

tph-1 : zag-1

HSN GFP expression was rare or absent in zag-1 tph-1::gfp adult animals, whereas expression was unchanged in ADF, NSM, CP and R(1,3,9).

sop-2 : tph-1

In wild-type males, the reporter is expressed in all six CP neurons. In sop-2(bx91) males, it is expressed in an average of 2.3 ventral cord cells.

brc-1 : hsr-9

In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).

brc-1 : polq-1

In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).

brc-1 : hsr-9

In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).

brd-1 : hsr-9

In contrast to what has been reported in mice, we observed elevated embryonic lethality in brc-1 and brd-1 null alleles [brc-1(xoe4), brd-1(xoe18) (Li et al. 2023; Li et al. 2018)], in combination with either hsr-9(ok759) (Ryu et al. 2013) or a new putative null allele hsr-9(xoe17) (Figure 1A).

brc-1 : hsr-9

On the other hand, a hypomorphic brc-1 allele, brc-1(tm1145) (Li et al. 2018), in combination with hsr-9(xoe17) did not result in elevated embryonic lethality (Figure 1A).

med-1 : oma-1

A Pmed-1gfp reporter construct expresses GFP exclusively in MS and E, the daughters of EMS, and their descendants. When the Pmed-1::gfp reporter was introduced into oma-1(zu405) mutant worms, GFP was consistently detected in the descendants of the C blastomere, Ca and Cp, in addition to EMS descendents.