"we used cell-type-specific promoters driving green fluorescent protein (GFP) expression in neurons and muscle (Fig. 2, E to K).... The number of GFP-positive muscle nuclei was significantly reduced, which is consistent with cell death (Fig. 2K).
daf-2(
e1370) protected myocytes from both nuclear fragmentation and death (Fig. 2, H and K)... Hypoxia also reduced the number of GFP(+) neurons.
e1370 mutants did not show neuronal loss and axonal pathology (Fig. 2, J and K)."