"As described previously, DYN-1-GFP foci localize across the cortex before the onset of polarity establishment in wild-type embryos. The foci become enriched in the anterior and are maintained through cytokinesis (Figure 2C, control; Nakayama et_al, 2009)... To determine whether the disruption in DYN-1-GFP foci to the cortex was specific to Arp2/3-regulated actin dynamics, we again disrupted WAVE function through
gex-3 RNAi and quantified the number of DYN-1 foci at the cortex (Figure 2, C and D). We found that disruption of WAVE/SCAR function by
gex-3 RNAi also significantly reduces the number of DYN-1-GFP cortical foci, similar to
arx-2 RNAi, suggesting that localization of DYN-1 cortex relies on Arp2/3 and WAVE/SCAR-mediated actin dynamics."