Feminization with strong loss-of-function mutations in the sex determination pathway delayed the time of onset and the severity of oocyte degeneration in sacy-1(tm5503) females (Figure 8 and Figure S3; S. Kim and D. Greenstein, unpublished results).
These animals showed no hlh-8::gfp expression throughout the M lineage and lacked all M-derived CCs. This is an enhancement of the defects in the M-lineage compared to either RNAi or mutant alone.
These animals showed no hlh-8::gfp expression throughout the M lineage and lacked all M-derived CCs. This is an enhancement of the defects in the M-lineage compared to either RNAi or mutant alone.