Authors subjected animals carrying
hmp-2(
qm39) (Hardin et al., 2013; Hekimi et al., 1995), a hypomorphic allele of HMP-2/ b-catenin, to mild
ulp-2 RNAi by feeding, a method that results in low embryonic lethality in wild-type (WT) animals. These embryos displayed an enhanced phenotype consisting of increased bulge formation (Humpback phenotype) and embryonic lethality compared to
hmp-2 hypomorphs subjected to control RNAi.