madd-4 : nlg-1

"The Ig-like domain of N-MADD-4B is essential for the interaction with NLG-1 in vitro."

daf-2 : dnj-25 : srxa-6

The daf-2(e1368) mutation suppresses the induction of expression of the out-of-frame lacZ::gfp transgene, indicating an increase in genomic stability

sma-10 : sma-6 : sma-9

Two deletion alleles of sma-10, which encodes a conserved, leucine-rich repeats- and immuno- globulin (Ig)-like domain (LRIG)-containing transmembrane protein that promotes Sma/Mab signaling in regulating body size, do suppress the M lineage phenotype of sma-9(0) mutants.

dcs-1 : heat shock

"To examine the expression pattern of fre-1, we amplified the 1.8 kbp 5' to the dcs-1 open reading frame, the entire dcs-1 coding region, and the first 38 coding bp of fre-1 and cloned this construct in-frame with GFP. Examination of transgenic animals carrying this construct showed GFP expression throughout development in the nuclei of neurons and the pharyngeal muscle, with heat shock enhancing GFP expression (Fig. 4A). RT-PCR analysis of dcs-1 and fre-1 indicates that both mRNAs are expressed in all developmental stages, that L3 and adults have higher expression levels, and that both messages are present in dauer animals and similarly induced by heat shock (Fig. 4B)."

fre-1 : heat shock

"To examine the expression pattern of fre-1, we amplified the 1.8 kbp 5' to the dcs-1 open reading frame, the entire dcs-1 coding region, and the first 38 coding bp of fre-1 and cloned this construct in-frame with GFP. Examination of transgenic animals carrying this construct showed GFP expression throughout development in the nuclei of neurons and the pharyngeal muscle, with heat shock enhancing GFP expression (Fig. 4A). RT-PCR analysis of dcs-1 and fre-1 indicates that both mRNAs are expressed in all developmental stages, that L3 and adults have higher expression levels, and that both messages are present in dauer animals and similarly induced by heat shock (Fig. 4B)."

fre-1 : heat shock

"To examine the expression pattern of fre-1, we amplified the 1.8 kbp 5' to the dcs-1 open reading frame, the entire dcs-1 coding region, and the first 38 coding bp of fre-1 and cloned this construct in-frame with GFP. Examination of transgenic animals carrying this construct showed GFP expression throughout development in the nuclei of neurons and the pharyngeal muscle, with heat shock enhancing GFP expression (Fig. 4A). RT-PCR analysis of dcs-1 and fre-1 indicates that both mRNAs are expressed in all developmental stages, that L3 and adults have higher expression levels, and that both messages are present in dauer animals and similarly induced by heat shock (Fig. 4B)."

dcs-1 : heat shock

"To examine the expression pattern of fre-1, we amplified the 1.8 kbp 5' to the dcs-1 open reading frame, the entire dcs-1 coding region, and the first 38 coding bp of fre-1 and cloned this construct in-frame with GFP. Examination of transgenic animals carrying this construct showed GFP expression throughout development in the nuclei of neurons and the pharyngeal muscle, with heat shock enhancing GFP expression (Fig. 4A). RT-PCR analysis of dcs-1 and fre-1 indicates that both mRNAs are expressed in all developmental stages, that L3 and adults have higher expression levels, and that both messages are present in dauer animals and similarly induced by heat shock (Fig. 4B)."

kal-1 : sax-7

"KAL-1/anosmin-1 mediates neurite branching as an autocrine co-factor with EGL-17/FGF through a receptor complex consisting of the conserved cell adhesion molecule SAX-7/L1CAM and the fibroblast growth factor receptor EGL-15/FGFR. This protein complex, which appears conserved in humans, requires the immunoglobulin (Ig) domains of SAX-7/L1CAM and the FN(III) domains of KAL-1/anosmin-1 for formation in vitro as well as function in vivo."

egl-15 : kal-1

"KAL-1/anosmin-1 mediates neurite branching as an autocrine co-factor with EGL-17/FGF through a receptor complex consisting of the conserved cell adhesion molecule SAX-7/L1CAM and the fibroblast growth factor receptor EGL-15/FGFR. This protein complex, which appears conserved in humans, requires the immunoglobulin (Ig) domains of SAX-7/L1CAM and the FN(III) domains of KAL-1/anosmin-1 for formation in vitro as well as function in vivo."

egl-15 : sax-7

"KAL-1/anosmin-1 mediates neurite branching as an autocrine co-factor with EGL-17/FGF through a receptor complex consisting of the conserved cell adhesion molecule SAX-7/L1CAM and the fibroblast growth factor receptor EGL-15/FGFR. This protein complex, which appears conserved in humans, requires the immunoglobulin (Ig) domains of SAX-7/L1CAM and the FN(III) domains of KAL-1/anosmin-1 for formation in vitro as well as function in vivo."