mes-4(
bn23) suppresses the embryonic lethality of
pos-1 RNAi. The authors suggest that this is due to disabling of the RNAi machinery by the
mes-4(
bn23) loss-of-function mutant. Note: the
mes-4 loss of function cannot suppress the embryonic lethality of
pos-1 RNAi when worms are soaked in low concentrations (~100ng/ul) of
pos-1 dsRNA