Expression level of sod-3 mRNA decreased (0.5-fold) in cholesterol starvation (CS) as compared to those of worms grown in cholesterol normal feeding (CN).
High-levels of hsp-16.2 mRNAs were induced (11.4-fold) in cholesterol starvation (CS) as compared to those of worms grown in cholesterol normal feeding (CN).
High-levels of hsp-16.1 mRNAs were induced (3.8-fold) in cholesterol starvation (CS) as compared to those of worms grown in cholesterol normal feeding (CN).
The mRNA level of daf-12, which encodes a predicted nuclear hormone receptor and its unliganded form was shown to induce DAF-16 translocation, increased 1.9-fold in cholesterol starvation (CS) compared to cholesterol normal feeding (CN).
The mRNA level of daf-9, encoding a cytochrome P450 that likely converts cholesterol to a hormonal signal for DAF-12, also increased 1.6-fold in cholesterol starvation(CS) compared to cholesterol normal feeding(CN).
ACDH-1 (Short-chain acyl-CoA dehydrogenase), and CE12564 (R07H5.8, adenosine kinase) is down-regulated in cholesterol starvation. Proteins function- ing in protein synthesis that were also down-regulated in CS were CE01270 (EEF-1A.1, eukaryotic translation elongation factor EF-1-alpha) and CE09655 (RLA-0, ribosomal protein, large subunit)