Mn uptake was increased due to deletion of djr1.1, whereas the elemental distribution of Mn was altered significantly in the djr1.1, djr1.2 double deletion mutants.
Mutants containing a-Syn accumulated less Mn compared to the deletion mutant alone, the decrease in accumulation was significant at 7.5 and 10 mM Mn for the djr1.1 mutants.
One-way ANOVA analysis showed a significantly increased sensitivity of the a-Syn-containing djr1.1 mutants towards Mn compared to the djr1.1 mutants alone