"Several genes, of which induction by tunicamycin is dependent on xbp-1 and ire-1, were found to be downregulated in pept-1 (e.g., T14G8.3, Y41C4A.11, K01D12.11, B0285.9, and ZC239.12)."
Increased expression levels of oxidation-related enzymes (e.g., SAMS-4, EFT-2, cyp-13A8, and rpt-1) appears to result in increased ROS production and reduced oxidative stress resistance in lbp-5(tm1618) mutant worms.
"Mutants that lack endogenous serotonin (e.g.,cat-4) and wild-type animals treated with the serotonin antagonist methiothepin had a slight increase in the number of UNC-13S::GFP puncta (Figure 5B and Table 3)."
Increased expression levels of oxidation-related enzymes (e.g., SAMS-4, EFT-2, cyp-13A8, and rpt-1) appears to result in increased ROS production and reduced oxidative stress resistance in lbp-5(tm1618) mutant worms.
Increased expression levels of oxidation-related enzymes (e.g., SAMS-4, EFT-2, cyp-13A8, and rpt-1) appears to result in increased ROS production and reduced oxidative stress resistance in lbp-5(tm1618) mutant worms.
Increased expression levels of oxidation-related enzymes (e.g., SAMS-4, EFT-2, cyp-13A8, and rpt-1) appears to result in increased ROS production and reduced oxidative stress resistance in lbp-5(tm1618) mutant worms.
"Mutants that lack endogenous serotonin (e.g.,cat-4) and wild-type animals treated with the serotonin antagonist methiothepin had a slight increase in the number of UNC-13S::GFP puncta (Figure 5B and Table 3)."
"In smg-1(r861) (lanes 2,4,6,8), the steady-state level of unproductively spliced rpl mRNAs is substantially elevated and often equals or exceeds that of the productively spliced counterpart (e.g., rpl-3, lane 8 and rpl-7a, lane 2)."
"In smg-1(r861) (lanes 2,4,6,8), the steady-state level of unproductively spliced rpl mRNAs is substantially elevated and often equals or exceeds that of the productively spliced counterpart (e.g., rpl-3, lane 8 and rpl-7a, lane 2)."