end-1,3(RNAi) embryos, isolated E blastomeres that do not produce endoderm instead produce body wall muscle and epidermis, characteristic of the C cell, a cousin of E.
sdc-3 mutations result in greatly elevated her-1 RNA levels in X X animals, consistent with the masculinization of sdc-3 mutants and sdc-3's proposed role as a negative regulator of her-1.