hepatic stellate cell proliferation

The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.

regulation of hepatic stellate cell proliferation

Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.

negative regulation of hepatic stellate cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.

positive regulation of hepatic stellate cell proliferation

Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.

symbiont-mediated disruption of host cell-cell adhesion

A process in which a symbiont alters or subverts host cell adhesion ito its extracellular matrix. The host is defined as the larger of the organisms involved in a symbiotic interaction.

pancreatic A cell fate commitment

The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.

phosphatidylethanolamine-sterol O-acyltransferase activity

Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.

phosphatidate-sterol O-acyltransferase activity

Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.

D-2-hydroxyacid dehydrogenase (quinone) activity

Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol.

protein serine/threonine phosphatase complex

A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.