super elongation complex

A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.

pancreatic A cell fate commitment

The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.

phosphatidylethanolamine-sterol O-acyltransferase activity

Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.

phosphatidate-sterol O-acyltransferase activity

Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.

D-2-hydroxyacid dehydrogenase (quinone) activity

Catalysis of the reaction: a (2R)-2-hydroxycarboxylate + a quinone = a 2-oxocarboxylate + a quinol.

protein serine/threonine phosphatase complex

A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.

protein localization to mast cell secretory granule

A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.

nucleoside phosphotransferase activity

Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.

semaphorin receptor complex

A stable binary complex of a semaphorin and a plexin, together forming a functional semaphorin receptor.

protein localization to T cell secretory granule

A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.