adaptive immune effector response involving T cells and B lineage cells

An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.

lymphocyte costimulation

The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.

helper T cell enhancement of B cell mediated immune response

Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.

establishment of granzyme B localization to T cell secretory granule

The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.

inflammatory response to antigenic stimulus

An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.

antigen receptor-mediated signaling pathway

The series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.

primary adaptive immune response involving T cells and B cells

An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.

CD27 receptor binding

Binding to a CD27, a receptor found on the surface of T cells and some B cells and NK cells.

CD70 receptor binding

Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells.

peripheral B cell positive selection

Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.