Enables several functions, including identical protein binding activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Involved in several processes, including nuclear division; pronuclear migration; and regulation of actomyosin contractile ring contraction. Located in cleavage furrow; microtubule cytoskeleton; and midbody. Part of centralspindlin complex. Expressed in germ cell and gonad. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type III. Is an ortholog of human KIF23 (kinesin family member 23).
Enables GTPase activator activity. Involved in mitotic cleavage furrow ingression; mitotic spindle midzone assembly; and polar body extrusion after meiotic divisions. Located in mitotic spindle midzone and plasma membrane. Part of centralspindlin complex. Expressed in germ cell; gonad; and tail. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia. Is an ortholog of human RACGAP1 (Rac GTPase activating protein 1).
Enables ATPase binding activity; kinesin binding activity; and protein kinase activity. Involved in several processes, including chromosome condensation; regulation of actomyosin contractile ring contraction; and spindle midzone assembly. Located in condensed nuclear chromosome and spindle midzone. Expressed in oocyte and sperm. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); invasive ductal carcinoma; and prostate carcinoma in situ. Is an ortholog of human AURKB (aurora kinase B).
Enables RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in positive regulation of gene expression. Located in endoplasmic reticulum and intracellular non-membrane-bounded organelle. Part of ribonucleoprotein complex. Expressed in germ line; gonad; neurons; somatic cell; and touch receptor neurons. Is an ortholog of human LSM14B (LSM family member 14B).