nrfl-1

Caenorhabditis elegans

Enables protein-membrane adaptor activity. Predicted to be involved in protein localization to plasma membrane. Located in apical plasma membrane. Expressed in excretory canal; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in hypophosphatemic nephrolithiasis/osteoporosis 2. Is an ortholog of human NHERF1 (NHERF family PDZ scaffold protein 1) and NHERF2 (NHERF family PDZ scaffold protein 2).