Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 8. Is an ortholog of human TACO1 (translational activator of cytochrome c oxidase I).
Predicted to enable ligand-gated sodium channel activity. Involved in locomotion and neuron remodeling. Located in neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma).
Predicted to be involved in intrinsic apoptotic signaling pathway. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 17. Is an ortholog of human COA8 (cytochrome c oxidase assembly factor 8).