Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including neuromuscular synaptic transmission; positive regulation of acetylcholine secretion, neurotransmission; and regulation of multicellular organismal process. Located in neuron projection; neuronal cell body; and postsynaptic membrane. Expressed in body wall musculature; head neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; autosomal dominant nocturnal frontal lobe epilepsy 1; and congenital myasthenic syndrome (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA4 (cholinergic receptor nicotinic alpha 4 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit).
Involved in several processes, including protein localization to nucleus; protein stabilization; and vulval development. Located in nucleus. Expressed in somatic cell.
Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell.
Involved in regulation of axon extension and regulation of synapse organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in CAN; HSN; ganglia; somatic nervous system; and touch receptor neurons. Is an ortholog of human SCOC (short coiled-coil protein).
Enables gap junction channel activity. Involved in several processes, including regulation of multicellular organismal process; reproductive behavior; and response to anesthetic. Located in gap junction and neuron projection membrane. Expressed in several structures, including OL socket cell; intestine; muscle cell; neurons; and pharyngeal gland cell.