Bma-prp-3

Brugia malayi

Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Is an ortholog of C. elegans prp-3.

Bma-unc-3

Brugia malayi

Predicted to enable DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans unc-3. In C. elegans, unc-3 is involved in several processes, including dauer larval development; neuron differentiation; and positive regulation of transcription by RNA polymerase II.

Bm5635

Brugia malayi

Is predicted to encode a protein with the following domains: Transmembrane Fragile-X-F-associated protein and Transmembrane Fragile-X-F protein. Is an ortholog of C. elegans T07A9.12.

Bm7306

Brugia malayi

Is predicted to encode a protein with the following domains: Transmembrane Fragile-X-F-associated protein and Transmembrane Fragile-X-F protein. Is an ortholog of C. elegans Y116A8C.9.

Bm7540

Brugia malayi

Predicted to be part of troponin complex. Is an ortholog of C. elegans tni-1; tni-3; and unc-27. In C. elegans, tni-1 is involved in backward locomotion.

Bma-unc-93

Brugia malayi

Enriched in reproductive tract based on proteomic studies. Is predicted to encode a protein with the following domains: Ion channel regulatory protein UNC-93; MFS transporter superfamily; Ion channel regulatory protein, UNC-93; Ankyrin repeat; Zinc finger, RING/FYVE/PHD-type; BRCT domain superfamily; Ankyrin repeat-containing domain superfamily; and Ankyrin repeats (3 copies). Is an ortholog of C. elegans unc-93. In C. elegans, unc-93 is involved in regulation of muscle contraction and regulation of potassium ion transport.

Bma-unc-50

Brugia malayi

Is predicted to encode a protein with the following domains: UNC-50 and UNC-50 family. Is an ortholog of C. elegans unc-50. In C. elegans, unc-50 is involved in receptor localization to synapse and regulation of muscle contraction.

Bm10299

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain.

Bma-unc-46

Brugia malayi

Is an ortholog of C. elegans unc-46.

Bm2981

Brugia malayi

Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans ZK418.10; Y47D7A.3; and unc-55.