Enables SH3 domain binding activity; cytoskeletal protein binding activity; and protein kinase binding activity. Involved in several processes, including positive regulation of ovulation; positive regulation of sarcomere organization; and skeletal muscle myosin thick filament assembly. Located in A band and myosin filament. Expressed in alimentary muscle; body wall musculature; gonad; vulval muscle; and in male. Is an ortholog of human MYH16 (myosin heavy chain 16).
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 15. Is an ortholog of human NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4).
Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell.
Is affected by several genes including npr-15; unc-30; and plp-1 based on RNA-seq studies. Is affected by four chemicals including atracurium; bortezomib; and Tamoxifen based on RNA-seq studies.
Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including npr-15; ins-11; and unc-30 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies.