unc-13

Caenorhabditis elegans

Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in regulation of multicellular organismal process; spermatogenesis; and synaptic vesicle exocytosis. Located in presynaptic active zone. Expressed in head neurons; neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human UNC13C (unc-13 homolog C).

F54G2.1

Caenorhabditis elegans

Predicted to be located in secretory vesicle. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 3. Is an ortholog of human BAIAP3 (BAI1 associated protein 3) and UNC13D (unc-13 homolog D).

sup-6

Caenorhabditis elegans

Is affected by several genes including ptl-1; ptrn-1; and etr-1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin and sodium arsenite based on RNA-seq studies.

aex-1

Caenorhabditis elegans

Involved in several processes, including positive regulation of intestinal lipid absorption; positive regulation of transport; and reproductive behavior. Predicted to be located in exocytic vesicle. Expressed in amphid neurons; body wall musculature; and intestine.

Y55F3AM.13

Caenorhabditis elegans

Enriched in germ line; rectal epithelial cell; rectum; and somatic gonad precursor based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; myrf-1; and nuo-6 based on microarray; proteomic; and RNA-seq studies. Is affected by six chemicals including rifampin; allantoin; and Capsaicin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.

seu-2

Caenorhabditis elegans

Acts upstream of or within dorsal/ventral axon guidance.

seu-3

Caenorhabditis elegans

Acts upstream of or within dorsal/ventral axon guidance.

unc-96

Caenorhabditis elegans

Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell.

F07A11.12

Caenorhabditis elegans

Is affected by several genes including hpl-2; unc-39; and unc-30 based on RNA-seq studies.

unc-69

Caenorhabditis elegans

Involved in regulation of axon extension and regulation of synapse organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in CAN; HSN; ganglia; somatic nervous system; and touch receptor neurons. Is an ortholog of human SCOC (short coiled-coil protein).