C27C7.2

Caenorhabditis elegans

Is affected by ubc-9; sir-2.1; and mrps-5 based on microarray studies. Is affected by resveratrol based on microarray studies.

ubc-15

Caenorhabditis elegans

Enables ubiquitin protein ligase binding activity. Predicted to be involved in protein modification by small protein conjugation.

ubc-18

Caenorhabditis elegans

Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in several processes, including determination of adult lifespan; embryonic digestive tract morphogenesis; and ubiquitin-dependent protein catabolic process. Acts upstream of or within animal organ morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5).

ubc-22

Caenorhabditis elegans

Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in nucleus.

ubc-7

Caenorhabditis elegans

Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Is an ortholog of human UBE2G1 (ubiquitin conjugating enzyme E2 G1).

ubc-1

Caenorhabditis elegans

Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in DNA repair and protein ubiquitination. Part of ubiquitin conjugating enzyme complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Is an ortholog of human UBE2B (ubiquitin conjugating enzyme E2 B).

ubc-13

Caenorhabditis elegans

Contributes to ubiquitin-protein transferase activity. Involved in protein ubiquitination and regulation of protein localization to cell surface. Part of ubiquitin conjugating enzyme complex. Expressed in several structures, including intestinal cell. Is an ortholog of human UBE2N (ubiquitin conjugating enzyme E2 N) and UBE2NL (ubiquitin conjugating enzyme E2 N like (gene/pseudogene)).

hpo-37

Caenorhabditis elegans

Is affected by cyc-1; ubc-9; and ain-1 based on microarray studies. Is affected by Tunicamycin based on microarray studies.

ubc-3

Caenorhabditis elegans

Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Is an ortholog of human CDC34 (cell division cycle 34, ubiqiutin conjugating enzyme) and UBE2R2 (ubiquitin conjugating enzyme E2 R2).

ubc-6

Caenorhabditis elegans

Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in ERAD pathway and protein polyubiquitination. Predicted to be located in nucleus. Expressed in germ line and oocyte. Is an ortholog of human UBE2J1 (ubiquitin conjugating enzyme E2 J1).