ads-1

Caenorhabditis elegans

Predicted to enable FAD binding activity and alkylglycerone-phosphate synthase activity. Predicted to be involved in ether lipid biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 3. Is an ortholog of human AGPS (alkylglycerone phosphate synthase).

coa-7

Caenorhabditis elegans

Predicted to be located in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in spinocerebellar ataxia with axonal neuropathy type 3. Is an ortholog of human COA7 (cytochrome c oxidase assembly factor 7).

H43I07.1

Caenorhabditis elegans

Predicted to be involved in regulation of lipid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 3 and optic atrophy 3. Is an ortholog of human OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3).

sec-15

Caenorhabditis elegans

Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be part of exocyst. Expressed in embryonic cell; excretory canal; and hypodermis. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 3. Is an ortholog of human EXOC6B (exocyst complex component 6B).

zipt-13

Caenorhabditis elegans

Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 3. Is an ortholog of human SLC39A13 (solute carrier family 39 member 13).

T02H6.11

Caenorhabditis elegans

Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 3. Is an ortholog of human UQCRB (ubiquinol-cytochrome c reductase binding protein).

T19B10.5

Caenorhabditis elegans

Predicted to be located in membrane and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Is an ortholog of human AHNAK2 (AHNAK nucleoprotein 2) and PRX (periaxin).

sqd-1

Caenorhabditis elegans

Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 3 and hepatocellular carcinoma. Is an ortholog of human HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B) and HNRNPDL (heterogeneous nuclear ribonucleoprotein D like).

piki-1

Caenorhabditis elegans

Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in several processes, including phagosome maturation involved in apoptotic cell clearance; phosphatidylinositol-3-phosphate biosynthetic process; and positive regulation of phagocytosis, engulfment. Located in early phagosome and pseudopodium. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) and PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta).

snpc-4

Caenorhabditis elegans

Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in protein folding. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Expressed in germ cell; head neurons; intestine; and somatic gonad. Is an ortholog of human SNAPC4 (small nuclear RNA activating complex polypeptide 4).