Enables protein homodimerization activity; signaling receptor binding activity; and ubiquitin-protein transferase activity. Involved in cell projection organization; protein ubiquitination; and regulation of protein localization. Located in several cellular components, including cell leading edge; neuronal cell body; and striated muscle dense body. Expressed in several structures, including anchor cell; intestinal cell; muscle cell; neurons; and ray precursor cell. Used to study Opitz GBBB syndrome. Human ortholog(s) of this gene implicated in Opitz GBBB syndrome; anencephaly; and non-syndromic X-linked intellectual disability 101. Is an ortholog of human TRIM67 (tripartite motif containing 67) and TRIM9 (tripartite motif containing 9).
Involved in microtubule cytoskeleton organization. Located in cytoplasm and nucleus. Expressed in nervous system; pharynx; and vulva. Is an ortholog of human TXNDC9 (thioredoxin domain containing 9).
Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; intestine; nerve ring; and neurons.