Bma-top-3

Brugia malayi

Predicted to enable DNA binding activity; DNA topoisomerase type I (single strand cut, ATP-independent) activity; and zinc ion binding activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans top-3. In C. elegans, top-3 is involved in DNA topological change.

Bm7859

Brugia malayi

Predicted to enable ATP binding activity; DNA binding activity; and DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans cin-4 and top-2. In C. elegans, top-2 is involved in mitotic sister chromatid separation.

Bm5019

Brugia malayi

Predicted to enable ATP binding activity; DNA binding activity; and DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans cin-4 and top-2. In C. elegans, top-2 is involved in mitotic sister chromatid separation.

Bm10299

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain.

Bma-top-1

Brugia malayi

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Predicted to be located in chromosome. Is an ortholog of C. elegans top-1.

Bma-ftt-2.1

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain. Is an ortholog of C. elegans M117.3; ftt-2; and par-5. In C. elegans, ftt-2 is involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus.

Bma-ftt-2.2

Brugia malayi

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain. Is an ortholog of C. elegans M117.3; ftt-2; and par-5. In C. elegans, ftt-2 is involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus.

Bma-ints-3

Brugia malayi

Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: Integrator complex subunit 3 N-terminal; Integrator complex subunit 3, N-terminal; and Integrator complex subunit 3. Is an ortholog of C. elegans ints-3.

Bma-gpdh-3

Brugia malayi

Predicted to enable calcium ion binding activity and glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in glycerol-3-phosphate metabolic process. Is an ortholog of C. elegans gpdh-3.

Bm5782

Brugia malayi

Is predicted to encode a protein with the following domains: Resistance to inhibitors of cholinesterase protein 3; Resistance to inhibitors of cholinesterase homologue 3; and Resistance to inhibitors of cholinesterase protein 3, N-terminal.