tir-1

Caenorhabditis elegans

Enables several functions, including NAD+ nucleosidase activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including NAD catabolic process; defense response to other organism; and regulation of gene expression. Acts upstream of or within serotonin biosynthetic process. Located in axon cytoplasm and cell body. Expressed in head. Used to study amyotrophic lateral sclerosis. Is an ortholog of human SARM1 (sterile alpha and TIR motif containing 1).

tsp-16

Caenorhabditis elegans

Predicted to be located in membrane. Is an ortholog of human UPK1B (uroplakin 1B).

eas-1

Caenorhabditis elegans

Involved in Golgi vesicle transport. Located in cis-Golgi network. Expressed widely. Is an ortholog of human GOLT1A (golgi transport 1A) and GOLT1B (golgi transport 1B).

zchc-1A

Caenorhabditis elegans

Predicted to enable metal ion binding activity. Is an ortholog of human ZC2HC1A (zinc finger C2HC-type containing 1A) and ZC2HC1B (zinc finger C2HC-type containing 1B).

C27D6.11

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

tag-344

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

Y38H8A.4

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3).

snt-1

Caenorhabditis elegans

Enables calcium ion binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Involved in several processes, including defecation; regulation of nematode pharyngeal pumping; and synaptic vesicle endocytosis. Located in synaptic vesicle. Expressed in several structures, including excretory gland cell; gonad; nervous system; pharyngeal gland cell; and rectal gland cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Is an ortholog of human SYT1 (synaptotagmin 1).

exos-3

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1B and stomach cancer. Is an ortholog of human EXOSC3 (exosome component 3).

F32B5.1

Caenorhabditis elegans

Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to be located in extracellular space. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B).