Enables sequence-specific DNA binding activity. Involved in cell fate specification; chordate pharyngeal muscle development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in several structures, including MSaa; MSpa; MSpp; head neurons; and intestine.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin.
Enables DNA-binding transcription repressor activity; core promoter sequence-specific DNA binding activity; and enzyme binding activity. Involved in several processes, including muscle structure development; neuron migration; and olfactory behavior. Located in cytoplasm and nucleus. Expressed in amphid neurons; body wall musculature; head neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); ulnar-mammary syndrome; and vertebral anomalies and variable endocrine and T-cell dysfunction. Is an ortholog of human TBX2 (T-box transcription factor 2) and TBX3 (T-box transcription factor 3).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin.