tat-5

Caenorhabditis elegans

Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in embryo development. Located in cytoplasmic vesicle and plasma membrane. Expressed widely. Is an ortholog of human ATP9B (ATPase phospholipid transporting 9B (putative)).

tat-6

Caenorhabditis elegans

Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in endocytosis; phospholipid translocation; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endosome; plasma membrane; and trans-Golgi network. Expressed in anterior spermathecal-uterine core cell; gonad; head; and tail. Is an ortholog of human ATP9B (ATPase phospholipid transporting 9B (putative)).

tat-3

Caenorhabditis elegans

Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in sterol metabolic process. Predicted to be located in plasma membrane. Expressed in several structures, including XXX cell; anchor cell; distal tip cell; pharynx; and vulva. Is an ortholog of human ATP10A (ATPase phospholipid transporting 10A (putative)) and ATP10D (ATPase phospholipid transporting 10D (putative)).

tat-4

Caenorhabditis elegans

Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in sterol metabolic process. Predicted to be located in plasma membrane. Expressed in hermaphrodite gonad; intestine; pharyngeal-intestinal valve; and rectal gland cell. Is an ortholog of human ATP10A (ATPase phospholipid transporting 10A (putative)); ATP10B (ATPase phospholipid transporting 10B (putative)); and ATP10D (ATPase phospholipid transporting 10D (putative)).

tat-1

Caenorhabditis elegans

Enables ATPase-coupled intramembrane lipid transporter activity. Involved in several processes, including lysosome organization; phospholipid translocation; and regulation of phagocytosis, engulfment. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and endosome. Expressed in several structures, including intestine. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome. Is an ortholog of human ATP8A2 (ATPase phospholipid transporting 8A2).

tat-2

Caenorhabditis elegans

Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in sterol metabolic process. Predicted to be located in plasma membrane and trans-Golgi network. Expressed in several structures, including excretory system; gonad; pharynx; rectal gland cell; and vulva. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 1; intrahepatic cholestasis of pregnancy 1; and progressive familial intrahepatic cholestasis 1. Is an ortholog of human ATP8B4 (ATPase phospholipid transporting 8B4 (putative)).

tatn-1

Caenorhabditis elegans

Predicted to enable L-tyrosine:2-oxoglutarate aminotransferase activity. Involved in dauer entry. Human ortholog(s) of this gene implicated in tyrosinemia type II. Is an ortholog of human TAT (tyrosine aminotransferase).

cus-2

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be part of U2 snRNP and U2-type spliceosomal complex. Is an ortholog of human HTATSF1 (HIV-1 Tat specific factor 1).

C33F10.14

Caenorhabditis elegans

Predicted to enable NAD binding activity and oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Predicted to be involved in import into nucleus. Predicted to be located in cytoplasm. Is an ortholog of human HTATIP2 (HIV-1 Tat interactive protein 2).

pssy-1

Caenorhabditis elegans

Predicted to enable L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Is an ortholog of human PTDSS1 (phosphatidylserine synthase 1).