spl-2

Caenorhabditis elegans

Predicted to enable sphinganine-1-phosphate aldolase activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Is an ortholog of human SGPL1 (sphingosine-1-phosphate lyase 1).

hdl-2

Caenorhabditis elegans

Predicted to enable carboxy-lyase activity. Predicted to be involved in amino acid metabolic process and carboxylic acid metabolic process. Predicted to be located in cytoplasm.

lin-38

Caenorhabditis elegans

Involved in negative regulation of vulval development.

let-38

Caenorhabditis elegans

egli-1

Caenorhabditis elegans

Predicted to be involved in autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).

spe-38

Caenorhabditis elegans

Involved in sperm entry. Located in cell cortex. Expressed in sperm and spermatid.

ins-38

Caenorhabditis elegans

Expressed in coelomocyte; neurons; and ventral nerve cord.

gst-38

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Involved in PERK-mediated unfolded protein response and innate immune response. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase).

nas-38

Caenorhabditis elegans

Predicted to enable metalloendopeptidase activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in extracellular region.

tag-10

Caenorhabditis elegans

Located in membrane raft. Expressed in amphid neurons.