mtcl-1

Caenorhabditis elegans

Enriched in several structures, including GLR; head mesodermal cell; muscle cell; neurons; and rectal muscle based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including cyc-1; numr-2; and numr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Microtubule cross-linking factor 1-3. Is an ortholog of human MTCL1 (microtubule crosslinking factor 1) and MTCL2 (microtubule crosslinking factor 2). Human MTCL1 enables microtubule binding activity.

let-241

Caenorhabditis elegans

mir-241

Caenorhabditis elegans

Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in body wall musculature; excretory canal; hermaphrodite distal tip cell; and touch receptor neurons. Used to study Parkinson's disease.

egli-1

Caenorhabditis elegans

Predicted to be involved in autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).

tag-10

Caenorhabditis elegans

Located in membrane raft. Expressed in amphid neurons.

tag-120

Caenorhabditis elegans

Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).

hdl-2

Caenorhabditis elegans

Predicted to enable carboxy-lyase activity. Predicted to be involved in amino acid metabolic process and carboxylic acid metabolic process. Predicted to be located in cytoplasm.

F14D2.11

Caenorhabditis elegans

Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination.

F52C6.2

Caenorhabditis elegans

Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination.

tag-273

Caenorhabditis elegans

Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be located in actin cytoskeleton and plasma membrane. Is an ortholog of human LIMA1 (LIM domain and actin binding 1).