sorb-1

Caenorhabditis elegans

Involved in maintenance of mitochondrion location and sarcomere organization. Located in dense body; focal adhesion; and plasma membrane. Expressed in body wall musculature; non-striated muscle; and uterus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is an ortholog of human SORBS1 (sorbin and SH3 domain containing 1) and SORBS2 (sorbin and SH3 domain containing 2).

let-208

Caenorhabditis elegans

tmem-208

Caenorhabditis elegans

Predicted to be involved in vacuolar protein processing. Predicted to be located in endoplasmic reticulum membrane and vacuole. Is an ortholog of human TMEM208 (transmembrane protein 208).

egli-1

Caenorhabditis elegans

Predicted to be involved in autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).

tag-10

Caenorhabditis elegans

Located in membrane raft. Expressed in amphid neurons.

tag-120

Caenorhabditis elegans

Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).

hdl-2

Caenorhabditis elegans

Predicted to enable carboxy-lyase activity. Predicted to be involved in amino acid metabolic process and carboxylic acid metabolic process. Predicted to be located in cytoplasm.

F14D2.11

Caenorhabditis elegans

Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination.

F52C6.2

Caenorhabditis elegans

Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination.

tag-273

Caenorhabditis elegans

Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be located in actin cytoskeleton and plasma membrane. Is an ortholog of human LIMA1 (LIM domain and actin binding 1).