Enables protein tyrosine kinase activity. Involved in interneuron axon guidance; motor neuron axon guidance; and positive regulation of axon regeneration. Located in axon and plasma membrane. Expressed in DD neuron; SAB; hypodermis; rectal gland cell; and tail. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); carcinoma (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human DDR1 (discoidin domain receptor tyrosine kinase 1).
Predicted to enable serine-type endopeptidase activity. Involved in several processes, including axon regeneration; positive regulation of multicellular organismal process; and protein destabilization. Predicted to be located in extracellular space. Expressed in ADLL and ADLR. Human ortholog(s) of this gene implicated in enterokinase deficiency. Is an ortholog of human TMPRSS15 (transmembrane serine protease 15).
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Is an ortholog of human PFDN4 (prefoldin subunit 4).