Predicted to enable 3'-5'-RNA exonuclease activity. Involved in regulation of cell fate specification and regulation of development, heterochronic. Predicted to be located in P-body. Human ortholog(s) of this gene implicated in Perlman syndrome and nephroblastoma. Is an ortholog of human DIS3L2 (DIS3 like 3'-5' exoribonuclease 2).
Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including gamete generation; positive regulation of vulval development; and regulation of intracellular signal transduction. Predicted to be located in cytosol. Predicted to be part of preribosome, small subunit precursor. Expressed in gonad; nervous system; and vulva. Is an ortholog of human RIOK1 (RIO kinase 1).
Predicted to enable methylated histone binding activity. Predicted to be involved in cellular response to glucose starvation; rDNA heterochromatin formation; and regulation of transcription by glucose. Predicted to be located in nucleolus. Predicted to be part of chromatin silencing complex and rDNA heterochromatin. Expressed widely. Is an ortholog of human RRP8 (ribosomal RNA processing 8).