sur-4

Caenorhabditis elegans

sur-7

Caenorhabditis elegans

Involved in several processes, including cellular response to zinc ion; muscle cell cellular homeostasis; and positive regulation of Ras protein signal transduction. Located in endoplasmic reticulum membrane. Expressed in several structures, including hypodermis; muscle cell; pharynx; tail; and vulva.

sur-5

Caenorhabditis elegans

Predicted to enable acetoacetate-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; gonad; hypodermal cell; and somatic cell. Is an ortholog of human AACS (acetoacetyl-CoA synthetase).

sur-6

Caenorhabditis elegans

Predicted to enable protein phosphatase regulator activity. Involved in embryo development; nematode larval development; and positive regulation of vulval development. Predicted to be located in cytosol. Predicted to be part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; spinocerebellar ataxia type 12; and systemic lupus erythematosus. Is an ortholog of human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha) and PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta).

sur-2

Caenorhabditis elegans

Involved in defense response to Gram-positive bacterium; regulation of protein catabolic process; and regulation of transcription by RNA polymerase II. Part of mediator complex. Expressed in several structures, including P1.p; P2.p; P5.ppp; P7.paa; and vulval cell. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Is an ortholog of human MED23 (mediator complex subunit 23).

gld-4

Caenorhabditis elegans

Enables poly(A) RNA polymerase activity. Involved in cytosolic mRNA polyadenylation and positive regulation of meiotic cell cycle. Located in P granule. Expressed in Z2; Z3; and germ line. Is an ortholog of human TENT4A (terminal nucleotidyltransferase 4A) and TENT4B (terminal nucleotidyltransferase 4B).

sli-3

Caenorhabditis elegans

haly-1

Caenorhabditis elegans

Predicted to enable histidine ammonia-lyase activity. Involved in L-histidine catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in histidinemia. Is an ortholog of human HAL (histidine ammonia-lyase).

cdf-2

Caenorhabditis elegans

Predicted to enable zinc ion transmembrane transporter activity. Involved in cellular response to zinc ion and zinc ion transmembrane transport. Located in gut granule membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human SLC30A8 (solute carrier family 30 member 8).

dsl-1

Caenorhabditis elegans

Enables Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in plasma membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; P6.ppp; and vulval cell.