Is affected by several genes including ptl-1; ptrn-1; and etr-1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin and sodium arsenite based on RNA-seq studies.
Predicted to enable metalloendopeptidase activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of transforming growth factor beta receptor signaling pathway; and vulval development. Located in cytoplasmic vesicle membrane and plasma membrane. Expressed in M lineage cell; hypodermis; intestinal cell; spermatheca; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease 18; colorectal cancer; and reticulate acropigmentation of Kitamura. Is an ortholog of human ADAM10 (ADAM metallopeptidase domain 10).
Enables mRNA 3'-UTR binding activity. Involved in negative regulation of translation. Located in cytoplasm. Expressed in several structures, including gonad. Is an ortholog of human RBMS1 (RNA binding motif single stranded interacting protein 1); RBMS2 (RNA binding motif single stranded interacting protein 2); and RBMS3 (RNA binding motif single stranded interacting protein 3).
Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3).