spp-2

Caenorhabditis elegans

Involved in defense response to Gram-positive bacterium.

spp-12

Caenorhabditis elegans

Enables pore-forming activity. Involved in defense response to Gram-positive bacterium and pore formation in membrane of another organism. Part of pore complex. Expressed in I4 neuron; I6 neuron; M4 neuron; NSML; and NSMR.

spp-7

Caenorhabditis elegans

Expressed in head neurons; intestine; and pm7.

spp-4

Caenorhabditis elegans

Enriched in hypodermis; intestine; male-specific anatomical entity; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyc-1; nuo-6; and cua-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Heme; methylmercuric chloride; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin B type, region 2; Saposin-like type B, region 2; Saposin-like; Saposin B type domain; and Phosphorylation site.

spp-3

Caenorhabditis elegans

Enables identical protein binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in protein-containing complex. Expressed in SDQR.

spp-5

Caenorhabditis elegans

Enables channel activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium.

spp-1

Caenorhabditis elegans

Enables pore-forming activity. Involved in defense response to other organism and pore formation in membrane of another organism. Part of pore complex.

spp-10

Caenorhabditis elegans

Predicted to be involved in sphingolipid metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including cystic fibrosis; lung disease (multiple); and sphingolipidosis (multiple). Is an ortholog of human PSAP (prosaposin) and PSAPL1 (prosaposin like 1).

spp-6

Caenorhabditis elegans

Enriched in ALM; PLM; body wall muscle cell; and intestine based on tiling array; microarray; and RNA-seq studies. Is affected by several genes including etr-1; rsr-2; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin B type domain; Saposin B type, region 2; Saposin-like type B, region 2; and Saposin-like.

spp-20

Caenorhabditis elegans

Enriched in dopaminergic neurons and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including cyc-1; numr-2; and numr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including diallyl trisulfide; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin B type domain and Saposin-like.