Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Involved in several processes, including neuron remodeling; organelle localization; and regulation of cellular localization. Located in several cellular components, including kinetochore; nuclear envelope; and spindle pole. Expressed in germ cell; head; somatic cell; and tail. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2O; autosomal dominant intellectual developmental disorder 13; and spinal muscular atrophy with lower extremity predominant 1. Is an ortholog of human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1).
Involved in several processes, including homologous chromosome segregation; microtubule cytoskeleton organization; and vulval development. Located in mitochondrion.
Enables identical protein binding activity and molecular condensate scaffold activity. Involved in centrosome cycle; positive regulation of mitotic cell cycle, embryonic; and protein localization to organelle. Located in centrosome and cytoplasm.
Enables molecular adaptor activity and protein kinase binding activity. Involved in several processes, including centriole replication; embryo development; and vulval development. Located in centriole; cytoplasm; and pericentriolar material. Expressed in intestinal cell.
Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane.
Enables microtubule binding activity. Involved in several processes, including ciliary body morphogenesis; gonad development; and microtubule bundle formation involved in mitotic spindle midzone assembly. Located in microtubule; mitotic spindle midzone; and nucleus. Is an ortholog of human PRC1 (protein regulator of cytokinesis 1).