smu-2

Caenorhabditis elegans

Involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleolus. Expressed widely. Is an ortholog of human IK (IK cytokine).

smu-1

Caenorhabditis elegans

Enables protein homodimerization activity. Involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Expressed in several structures, including germ line. Is an ortholog of human SMU1 (SMU1 DNA replication regulator and spliceosomal factor).

rpap-2

Caenorhabditis elegans

Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human RPAP2 (RNA polymerase II associated protein 2).

crn-6

Caenorhabditis elegans

Enables deoxyribonuclease II activity. Involved in apoptotic DNA fragmentation. Is an ortholog of human DNASE2B (deoxyribonuclease 2 beta).

ceh-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in DVC; lateral ganglion; and seam cell. Is an ortholog of human NKX1-1 (NK1 homeobox 1) and NKX1-2 (NK1 homeobox 2).

efl-2

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in dorsal nerve cord; head muscle; intestine; spermatheca; and ventral nerve cord. Is an ortholog of human E2F6 (E2F transcription factor 6).

aman-2

Caenorhabditis elegans

Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in Golgi apparatus. Expressed in head; pharynx; and ventral nerve cord. Is an ortholog of human MAN2A2 (mannosidase alpha class 2A member 2).

C27F2.10

Caenorhabditis elegans

Predicted to enable RNA binding activity and double-stranded DNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; and transcription elongation by RNA polymerase II. Predicted to be part of transcription export complex 2. Is an ortholog of human PCID2 (PCI domain containing 2).

rpb-11

Caenorhabditis elegans

Predicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2J (RNA polymerase II subunit J); POLR2J2 (RNA polymerase II subunit J2); and POLR2J3 (RNA polymerase II subunit J3).

odd-2

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine. Is an ortholog of human OSR1 (odd-skipped related transcription factor 1) and OSR2 (odd-skipped related transciption factor 2).