Bma-smu-2.2

Brugia malayi

Is predicted to encode a protein with the following domains: Protein Red-like; Protein RED, C-terminal; RED-like protein C-terminal region; RED-like, N-terminal; and RED-like protein N-terminal region. Is an ortholog of C. elegans smu-2. In C. elegans, smu-2 is involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome.

Bma-smu-2.1

Brugia malayi

Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: Protein Red-like; Protein RED, C-terminal; RED-like protein C-terminal region; RED-like, N-terminal; and RED-like protein N-terminal region. Is an ortholog of C. elegans smu-2. In C. elegans, smu-2 is involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome.

Bma-smu-1

Brugia malayi

Predicted to be involved in mRNA splicing, via spliceosome. Is an ortholog of C. elegans smu-1. In C. elegans, smu-1 is involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome.

Bma-atf-2

Brugia malayi

Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans atf-2. In C. elegans, atf-2 is involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II.

Bma-ces-2

Brugia malayi

Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans ces-2. In C. elegans, ces-2 is involved in several processes, including apoptotic process; positive regulation of programmed cell death; and positive regulation of transcription by RNA polymerase II.

Bma-rpap-2

Brugia malayi

Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity and RNA polymerase core enzyme binding activity. Is an ortholog of C. elegans rpap-2.

Bma-efl-2

Brugia malayi

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein dimerization activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Is an ortholog of C. elegans efl-2.

Bm2533

Brugia malayi

Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans elt-2 and elt-4. In C. elegans, elt-2 is involved in several processes, including defense response to other organism; determination of adult lifespan; and positive regulation of transcription by RNA polymerase II.

Bm3641

Brugia malayi

Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of NURF complex. Is an ortholog of C. elegans baz-2 and nurf-1. In C. elegans, baz-2 is involved in epigenetic regulation of gene expression.

Bma-sur-2

Brugia malayi

Predicted to be involved in intracellular signal transduction. Is an ortholog of C. elegans sur-2. In C. elegans, sur-2 is involved in defense response to Gram-positive bacterium; regulation of protein catabolic process; and regulation of transcription by RNA polymerase II.