smp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in plasma membrane. Expressed in several structures, including hermaphrodite distal tip cell; non-striated muscle; ray; somatic nervous system; and vulval cell. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia; progressive myoclonus epilepsy; and rheumatoid arthritis. Is an ortholog of several human genes including SEMA3B (semaphorin 3B); SEMA3C (semaphorin 3C); and SEMA6C (semaphorin 6C).