Predicted to enable DNA binding activity. Involved in several processes, including nematode pharyngeal pumping; neuron fate specification; and serotonin receptor signaling pathway. Predicted to be located in nucleus. Expressed in ABalapaaap; ABalappapp; AVJL; and AVJR. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); arthritis (multiple); and kidney cancer (multiple). Is an ortholog of several human genes including NPAS1 (neuronal PAS domain protein 1); SIM1 (SIM bHLH transcription factor 1); and SIM2 (SIM bHLH transcription factor 2).
Contributes to sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Expressed in pharyngeal cell. Is an ortholog of human NPAS4 (neuronal PAS domain protein 4).