Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in dauer larval development; regulatory ncRNA-mediated post-transcriptional gene silencing; and stress response to metal ion. Located in plasma membrane. Expressed in several structures, including intestine; pharyngeal-intestinal valve; pharynx; rectal valve cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); leukemia (multiple); and liver disease (multiple). Is an ortholog of human ABCC3 (ATP binding cassette subfamily C member 3).
Predicted to enable protein tyrosine phosphatase activity. Involved in dauer larval development. Located in plasma membrane. Expressed in XXXL; XXXR; and head. Human ortholog(s) of this gene implicated in artery disease (multiple); proliferative diabetic retinopathy; and type 2 diabetes mellitus. Is an ortholog of human PTPN1 (protein tyrosine phosphatase non-receptor type 1).
Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human ARL14EP (ADP ribosylation factor like GTPase 14 effector protein) and ARL14EPL (ADP ribosylation factor like GTPase 14 effector protein like).