mog-2

Caenorhabditis elegans

Enables U2 snRNA binding activity. Involved in feminization of hermaphroditic germ-line; germline cell cycle switching, mitotic to meiotic cell cycle; and mRNA 3'-splice site recognition. Located in nucleoplasm. Part of U2 snRNP. Human ortholog(s) of this gene implicated in connective tissue disease. Is an ortholog of human SNRPA1 (small nuclear ribonucleoprotein polypeptide A').

saps-1

Caenorhabditis elegans

Enables protein phosphatase binding activity. Involved in cortical actin cytoskeleton organization; establishment of mitotic spindle localization; and first cell cycle pseudocleavage. Located in astral microtubule and cell cortex. Is an ortholog of human PPP6R3 (protein phosphatase 6 regulatory subunit 3).

pph-6

Caenorhabditis elegans

Predicted to enable protein serine/threonine phosphatase activity. Involved in cortical actin cytoskeleton organization; establishment of mitotic spindle localization; and first cell cycle pseudocleavage. Located in astral microtubule and cell cortex. Is an ortholog of human PPP6C (protein phosphatase 6 catalytic subunit).

rnp-3

Caenorhabditis elegans

Predicted to enable U1 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in Alzheimer's disease; connective tissue disease; and disease of cellular proliferation. Is an ortholog of human SNRPA (small nuclear ribonucleoprotein polypeptide A) and SNRPB2 (small nuclear ribonucleoprotein polypeptide B2).

C39E9.12

Caenorhabditis elegans

Enriched in several structures, including ABplapaaapa; ABplapppapp; ABprapaaapa; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyd-1; cye-1; and htz-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SAP domain superfamily and SAP domain.

Y53G8AR.6

Caenorhabditis elegans

Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human SARNP (SAP domain containing ribonucleoprotein).

sap-49

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex and U2 snRNP. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Nager acrofacial dysostosis; cervical cancer; and endocrine gland cancer (multiple). Is an ortholog of human SF3B4 (splicing factor 3b subunit 4).

eri-1

Caenorhabditis elegans

Enables 3'-5'-RNA exonuclease activity. Involved in RNA metabolic process; regulation of gene expression; and sexual reproduction. Located in cytoplasm. Expressed in neurons and spermatheca. Is an ortholog of human ERI1 (exoribonuclease 1).

pqn-62

Caenorhabditis elegans

Enriched in body wall musculature; head mesodermal cell; muscle cell; nerve ring neurons; and uv1 based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including cyd-1; nuo-6; and cua-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: SAP domain superfamily.

C15F1.14

Caenorhabditis elegans

Is affected by cep-1; adr-1; and sftb-1 based on RNA-seq studies.