Ovo-gap-2

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Ras GTPase-activating protein; C2 domain; Rho GTPase activation protein; GTPase-activator protein for Ras-like GTPase; Ras GTPase-activating domain; and C2 domain superfamily. Is an ortholog of C. elegans gap-2. In C. elegans, gap-2 is involved in learning or memory and negative regulation of Ras protein signal transduction.

Ovo-gap-1

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Pleckstrin homology domain; Ras GTPase-activating protein; Rho GTPase activation protein; GTPase-activator protein for Ras-like GTPase; PH domain; Ras GTPase-activating domain; C2 domain superfamily; and PH-like domain superfamily. Is an ortholog of C. elegans gap-1. In C. elegans, gap-1 is involved in chemosensory behavior; learning or memory; and negative regulation of Ras protein signal transduction.

OVOC9926

Onchocerca volvulus

Predicted to enable ATP binding activity; ATP-dependent chromatin remodeler activity; and DNA binding activity. Predicted to be involved in chromatin remodeling. Is an ortholog of C. elegans chd-3 and let-418. In C. elegans, chd-3 is involved in cell fate determination; negative regulation of Ras protein signal transduction; and negative regulation of vulval development.

Ovo-ras-1

Onchocerca volvulus

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Is an ortholog of C. elegans ras-1. In C. elegans, ras-1 is involved in parturition and vulval development.

Ovo-rme-6

Onchocerca volvulus

Is predicted to encode a protein with the following domains: VPS9 domain superfamily; Rho GTPase activation protein; GTPase-activator protein for Ras-like GTPase; Ras GTPase-activating domain; VPS9 domain; and Vacuolar sorting protein 9 (VPS9) domain. Is an ortholog of C. elegans rme-6. In C. elegans, rme-6 is involved in endocytosis; molting cycle; and regulation of clathrin-dependent endocytosis.

Ovo-gei-4

Onchocerca volvulus

Is an ortholog of C. elegans gei-4. In C. elegans, gei-4 is involved in negative regulation of Ras protein signal transduction and negative regulation of vulval development.

Ovo-ras-2

Onchocerca volvulus

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Is an ortholog of C. elegans ras-2.

OVOC13456

Onchocerca volvulus

Is predicted to encode a protein with the following domains: P-loop containing nucleoside triphosphate hydrolase and Ras of Complex, Roc, domain of DAPkinase. Is an ortholog of C. elegans Y116A8C.10.

Ovo-cav-1

Onchocerca volvulus

Predicted to be involved in caveola assembly. Is an ortholog of C. elegans cav-1. In C. elegans, cav-1 is involved in Ras protein signal transduction; meiotic cell cycle; and regulation of egg-laying behavior.

Ovo-ftt-2

Onchocerca volvulus

Is predicted to encode a protein with the following domains: 14-3-3 protein; 14-3-3 domain superfamily; and 14-3-3 domain. Is an ortholog of C. elegans M117.3; ftt-2; and par-5. In C. elegans, ftt-2 is involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus.