- aex-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity and GTPase activity. Involved in exocytosis; positive regulation of defecation; and positive regulation of protein catabolic process. Located in synaptic vesicle. Expressed in ALML; ALMR; BDUL; BDUR; and neurons. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is an ortholog of human RAB27A (RAB27A, member RAS oncogene family).
- M57.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein prenyltransferase activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Predicted to be involved in prenylation. Predicted to be located in cytoplasm. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Is an ortholog of human RABGGTA (Rab geranylgeranyltransferase subunit alpha).
- rab-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activity. Involved in phagolysosome assembly involved in apoptotic cell clearance and phagosome acidification involved in apoptotic cell clearance. Located in early endosome; phagocytic vesicle; and trans-Golgi network. Expressed in gonadal sheath cell; hypodermis; intestine; and pharyngeal muscle cell. Is an ortholog of human RAB14 (RAB14, member RAS oncogene family).
- rab-6.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activity. Involved in cortical granule exocytosis and cuticle development. Located in Golgi cisterna and cortical granule. Expressed in several structures, including RIG; command interneuron; gonad; intestine; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family).
- ggtb-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable small GTPase binding activity and zinc ion binding activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Involved in PERK-mediated unfolded protein response. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Expressed in head; intestine; and tail. Is an ortholog of human RABGGTB (Rab geranylgeranyltransferase subunit beta).
- rep-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activator activity and Rab GDP-dissociation inhibitor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in cytosol and nucleus. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Expressed in alimentary muscle; body wall musculature; hypodermis; and neurons. Human ortholog(s) of this gene implicated in asthma and choroideremia. Is an ortholog of human CHM (CHM Rab escort protein) and CHML (CHM like Rab escort protein).
- rab-6.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables GTP binding activity. Involved in several processes, including early endosome to Golgi transport; positive regulation of feeding behavior; and protein stabilization. Located in Golgi trans cisterna. Expressed in several structures, including coelomocyte; command interneuron; gonad; pharynx; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family) and RAB6B (RAB6B, member RAS oncogene family).
- rab-21 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in early endosome. Is an ortholog of human RAB21 (RAB21, member RAS oncogene family).