mig-15

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including dorsal/ventral axon guidance; nematode larval development; and regulation of GABAergic synaptic transmission. Predicted to be located in cytoplasm. Expressed in several structures, including QL; QR; body wall musculature; pharynx; and somatic nervous system. Used to study epilepsy. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive intellectual developmental disorder 54; gastrointestinal system cancer (multiple); and hepatitis B. Is an ortholog of human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4); MINK1 (misshapen like kinase 1); and TNIK (TRAF2 and NCK interacting kinase).

mau-8

Caenorhabditis elegans

Expressed in body wall musculature; germ line; hypodermis; intestine; and pharynx. Is an ortholog of human PDC (phosducin) and PDCL (phosducin like).

Y48B6A.17

Caenorhabditis elegans

Is affected by several genes including puf-8; npr-8; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

set-8

Caenorhabditis elegans

Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus.

Y49F6B.20

Caenorhabditis elegans

Is affected by nhr-8 based on RNA-seq studies.

F19B6.9

Caenorhabditis elegans

Is affected by npr-8 based on RNA-seq studies.

flp-8

Caenorhabditis elegans

Involved in negative regulation of turning behavior involved in mating. Predicted to be located in extracellular region. Expressed in PVM; head; nerve ring; and tail.

sma-8

Caenorhabditis elegans

him-8

Caenorhabditis elegans

Involved in meiotic chromosome segregation. Located in X chromosome; condensed nuclear chromosome; and nuclear envelope.

K08F8.15

Caenorhabditis elegans

Is affected by hda-2 and nhr-8 based on RNA-seq studies.